Polynucleotides vs Exosomes: Which Is Better for Treating Dark Circles in Central London?

Introduction

You’re getting plenty of sleep. You’re eating well. But no matter what you do, those dark circles under your eyes won’t go away. If this sounds familiar, you’re not alone. Under-eye circles are one of the most common concerns we treat at Alcove Aesthetics by Dr Goziem in Central London.

Whether it’s pigmentation, thinning skin, or a tired, sunken look, dark circles can leave you looking older and more fatigued than you feel. And while makeup can temporarily conceal the issue, more and more people are looking for long-term solutions that actually improve the quality of the skin.

Two of the most advanced treatments we offer are polynucleotides and exosomes. Both are regenerative, injectable treatments that work beneath the surface to revitalise the under-eye area. But how do they compare, and which is right for you?

In this guide, we’ll explore the science behind each treatment, the results you can expect, and how to choose the best option for your skin.

What Causes Dark Circles?

Not all dark circles are the same. Understanding the cause behind yours is the first step to treating them effectively.

In many cases, dark circles are caused by a combination of factors including:

• Genetic pigmentation
• Thinning skin that reveals underlying blood vessels
• Volume loss that creates hollows and shadowing
• Dehydration and poor skin quality
• Chronic inflammation or oxidative stress

Because the under-eye area is delicate and prone to early ageing, even small changes in skin structure can make a noticeable difference. That’s why regenerative treatments like polynucleotides and exosomes are becoming the go-to for patients who want real improvements without filler or surgery.

What Are Polynucleotides?

Polynucleotides are bio-stimulatory molecules derived from DNA fragments, often sourced from salmon. They work by stimulating fibroblasts, the skin cells responsible for producing collagen and elastin.

In simpler terms, they tell your skin to heal, hydrate and regenerate.

When injected into the under-eye area, polynucleotides help:

• Improve skin thickness and elasticity
• Reduce crepiness and fine lines
• Calm inflammation
• Increase hydration
• Brighten tired, dull-looking eyes

This treatment is especially well-suited for people with very thin skin, early signs of ageing or pigmentation related to inflammation. It’s gentle, natural and builds results gradually over time.

At Alcove Aesthetics, we often recommend a course of three sessions spaced a few weeks apart. Many of our clients start to notice subtle yet visible improvements after the first two treatments.

What Are Exosomes?

Exosomes are tiny messenger particles released by cells. They contain powerful growth factors and signalling molecules that tell your skin how to repair itself.

In aesthetics, exosomes are derived from stem cells and used to deliver a concentrated boost of regenerative information directly into the skin.

Under the eyes, exosome therapy can:

• Improve skin quality and tone
• Increase collagen production
• Reduce inflammation
• Support cellular renewal
• Soften dark pigmentation and brighten the area

Exosomes are slightly more intensive than polynucleotides and often used when the skin needs a more comprehensive rejuvenation. They’re ideal for clients who have dullness, fine lines and loss of structure all at once.

At our clinic in Central London, exosomes are offered as a standalone treatment or combined with microneedling for enhanced penetration. A course of three is typical for optimal results.

How Do They Compare?

Both treatments work by improving the skin from within, but they have slightly different strengths.

Some patients even combine the two treatments for more comprehensive rejuvenation. During your consultation at Alcove Aesthetics, we’ll assess your skin and help you choose the best option or combination for your needs.

Why Choose Alcove Aesthetics by Dr Goziem

At Alcove Aesthetics in Central London, your skin is in expert hands. Dr Goziem is a dentist with a master’s degree in aesthetic medicine and over seven years of experience delivering natural-looking, subtle enhancements.

We specialise in skin-focused treatments for patients who want to look refreshed and well-rested, not frozen or overfilled. Everything we do is led by medical knowledge and a deep understanding of facial anatomy.

Our under-eye rejuvenation treatments are tailored to your exact concerns, whether that’s pigmentation, volume loss, or poor skin quality. Dr Goziem is known for her gentle technique, exceptional patient care and beautiful, undetectable results.

We’re based in Pall Mall, just moments from Westminster and St James’s. Our discreet and welcoming setting is ideal for clients seeking premium care in the heart of Central London.

What to Expect: Consultation to Results

Your journey starts with a detailed consultation where we assess the cause of your dark circles and recommend the right treatment approach.

• During Treatment: Polynucleotides and exosomes are injected with a fine needle or cannula. The procedure takes around 20 to 30 minutes and is relatively comfortable.
• After Treatment: You may experience slight redness or swelling for a day or two. Most clients return to normal activities right away.
• Results Timeline: Polynucleotides build gradually with each session. Exosomes may deliver results slightly faster, especially with microneedling. Both offer long-lasting improvement with good skin care.
• Cost:
  • Polynucleotides: £310 per session or £900 for a course of three
  • Exosomes: £450 per session or £1350 for a course of three

Ready to Refresh Your Under-Eyes?

If you’re tired of looking tired, it’s time to treat the cause, not just the symptoms. Book your consultation online with Dr Goziem at Alcove Aesthetics in Central London and discover what subtle, skin-first under-eye rejuvenation can do for you.