If you are searching for polynucleotides in Mayfair, you are likely looking for a treatment that improves skin quality at a deeper level rather than simply masking signs of ageing. At our doctor-led clinic in Central London, polynucleotides are one of the most requested treatments for patients who want healthier, stronger, more resilient skin with natural-looking results. This advanced regenerative treatment works by supporting your skin’s own repair processes, improving texture, elasticity, and overall radiance over time.
At Alcove Aesthetics, located just moments from Pall Mall in the heart of Mayfair, polynucleotides are prescribed and administered exclusively by Dr Goziem Onuchukwu, a GDC-registered clinician with over 7 years of experience in aesthetic medicine. Patients choose this treatment because it delivers subtle yet meaningful improvements, making skin look refreshed, rested, and naturally youthful without looking treated.
Introduction
Many patients come to our Mayfair aesthetic clinic feeling frustrated. Their skin looks tired, crepey, or dull despite good skincare and a healthy lifestyle. Fine lines linger, elasticity feels reduced, and the skin no longer bounces back as it once did. These concerns are common from the early 30s onwards and often worsen with stress, environmental exposure, and hormonal changes.
Polynucleotides are increasingly sought after because they address skin quality rather than surface appearance. Instead of filling or freezing, this treatment focuses on repair, hydration, and regeneration. At Alcove Aesthetics, our philosophy centres on natural results. We prioritise treatments that work with your skin biology, creating gradual improvements that look effortless and authentic.
What Are Polynucleotides and How Do They Work?
Polynucleotides are purified DNA fragments derived from natural sources. In aesthetic medicine, they are used for their regenerative and anti-inflammatory properties. Once administered into the skin, polynucleotides act as bio-stimulators, supporting tissue repair and improving the skin’s environment at a cellular level.
These molecules attract water, helping to deeply hydrate the skin, while also encouraging fibroblast activity. Fibroblasts are responsible for producing collagen and elastin, which are essential for firmness and elasticity. Over time, this process improves skin texture, strength, and resilience.
Dr Goziem recommends polynucleotides for patients who want long-term skin health rather than instant but short-lived results. With over 1,000 patients treated successfully, her approach is grounded in evidence-based medicine and precise technique. The treatment is particularly effective for delicate areas such as under the eyes, face, neck, and décolletage, where skin thinning and fine lines are most noticeable.
Many patients combine polynucleotides with other regenerative treatments such as PRP or advanced skin boosters to optimise results, depending on individual skin needs.
Benefits and Results of Polynucleotides
Patients choosing polynucleotides in Central London often notice gradual but significant improvements. Benefits include:
- Improved skin hydration and glow
- Smoother texture and refined pores
- Increased firmness and elasticity
- Reduced appearance of fine lines
- Healthier-looking under-eye skin
- Strengthened skin barrier over time
Most patients begin to see visible improvement within 2 to 3 weeks, with results continuing to develop over several months. A course of treatments delivers the most noticeable and long-lasting outcomes.
Why Choose Alcove Aesthetics in Mayfair?
Choosing where to have polynucleotides in Mayfair matters. At Alcove Aesthetics, every treatment is doctor-led and tailored. Dr Goziem holds a BDS and MSc in Aesthetic Medicine and is recognised as Best Anti-Ageing Practitioner Central London 2024 and 2025.
Our clinic on Pall Mall offers a discreet, calm environment for patients across Westminster, St James’s, and Knightsbridge. We are known for precision, honest advice, and personalised care. There is no one-size-fits-all approach. Each plan is designed around your skin, your goals, and realistic outcomes.
Your Polynucleotides Treatment Journey
Your journey begins with a comprehensive consultation. We assess skin quality, medical history, and aesthetic goals before recommending polynucleotides or alternative treatments where appropriate.
On treatment day, the skin is cleansed and prepared. Polynucleotides are administered carefully using advanced techniques to ensure comfort and accuracy. The appointment typically lasts around 30 minutes.
After treatment, you may notice mild redness or swelling, which usually settles within 24 to 48 hours. Follow-up appointments are included to monitor progress and optimise results. Many patients enhance outcomes by combining this treatment with Skin Boosters as part of a wider skin plan.
Recovery and Aftercare
Downtime is minimal. Most patients return to normal activities the same day or the following morning. We advise avoiding intense exercise, alcohol, and heat exposure for 24 hours. Skin continues to improve over the following weeks as regeneration takes place.
Cost and Transparency
At our Mayfair clinic, pricing is clear and transparent:
| Treatment | Price |
|---|---|
| 1 session | £330 |
| 3-session course | £900 |
A £50 booking deposit is required and redeemable against treatment cost. Package options are recommended for optimal results and long-term skin health.
Frequently Asked Questions
Are polynucleotides safe?
Yes. When prescribed and administered by a qualified doctor, polynucleotides have an excellent safety profile.
Is the treatment painful?
Most patients describe mild discomfort only. We use techniques to maximise comfort.
How long do results last?
Results build gradually and typically last several months. Maintenance treatments are advised.
Who is suitable for polynucleotides?
Ideal for patients with early ageing, thin skin, dullness, or under-eye concerns.
Can polynucleotides be combined with other treatments?
Yes. Many patients combine this with Microneedling or PRP for enhanced regeneration.
Closing
To book your personalised consultation with Dr Goziem Onuchukwu at Alcove Aesthetics, Pall Mall, London, call 07856962248 or book online here.
Individual results may vary. A full consultation with Dr Goziem Onuchukwu is required to determine suitability. All treatments are doctor-administered at Alcove Aesthetics, 120 Pall Mall, London SW1Y 5EA.
