The under eye area is one of the first places to show signs of ageing, especially for women in their 30s and 40s. Fine lines, crepiness, darkness and a tired look can develop even when the rest of the face still appears fresh. In Mayfair and Central London, more patients are now turning to regenerative treatments like PRP and polynucleotides to soften these concerns without fillers or surgery. At Alcove Aesthetics on Pall Mall, these two doctor led treatments are used to strengthen the delicate under eye skin, improve brightness and create a naturally rested look.
The aim of this guide is to explain exactly how PRP and polynucleotides work, what results you can expect, and why doctor led treatment is essential for this fragile area.
Introduction
The skin beneath the eyes is thinner, drier and more prone to collagen loss than any other part of the face. Even small changes in hydration or texture can make this area appear tired. Many patients come to Alcove Aesthetics seeking a solution that looks subtle, avoids puffiness and supports long term skin health. PRP and polynucleotides achieve this by improving the quality of the skin itself rather than masking concerns. Both treatments stimulate natural repair and can be used alone or together for enhanced results.
What It Is and How It Works
PRP
PRP uses your own platelets to support skin healing and regeneration. A small blood sample is taken and processed to isolate the platelet rich plasma. This concentrated plasma contains growth factors that encourage collagen production, enhance circulation and repair damaged tissue. When injected into the under eye area, PRP improves texture, reduces crepiness and softens fine lines without adding bulk.
Polynucleotides
Polynucleotides are purified DNA fragments derived from salmon sources. They work by boosting cellular repair, increasing hydration and improving the skin’s microenvironment. For the under eye area they offer three key benefits:
- increased fibroblast activity for firmer, healthier skin
- improved elasticity
- better water retention in the tissues, giving a smoother appearance
Polynucleotides also reduce inflammation, making them ideal for sensitive or crepey under eye skin.
You can learn more about how these molecules enhance collagen by visiting our Polynucleotides page:
https://alcoveaesthetics.com/polynulceotides-ameela/
Why They Work Well Together
PRP provides growth factors that instruct the skin to repair, while polynucleotides provide the structural support and hydration needed for that repair to be effective. The result is a stronger, brighter and smoother under eye area without filler heaviness.
Benefits and Results
Key benefits include:
- softer fine lines
- smoother texture
- improvement in under eye crepiness
- brighter, healthier looking skin
- subtle thickening of thin under eye tissue
- enhanced hydration and elasticity
- no change to natural facial contours
Results typically:
- start to appear after 2 to 4 weeks
- continue to improve over 8 to 12 weeks
- last several months with maintenance
Patients often describe looking more rested and awake, with makeup sitting more smoothly under the eyes.
Why Choose Alcove Aesthetics
Alcove Aesthetics by Dr Goziem is a doctor led facial aesthetics clinic in the heart of Central London at 120 Pall Mall. Under eye work requires precision, anatomical understanding and a conservative approach to keep results natural. Dr Goziem Onuchukwu, BDS, MSc (Aesthetic Medicine), brings more than 7 years of experience and has treated over 1,000 patients. She has been awarded Best Anti Ageing Practitioner in Central London for 2024 and 2025, as well as Skin Aesthetics Specialist of the Year 2025.
Patients choose the clinic for its combination of scientific expertise, careful technique and a calm, luxury setting that prioritises safety and natural results.
Treatment Journey
Consultation
Your visit begins with an in depth consultation to assess the under eye area, skin thickness, lifestyle factors and suitability for PRP and polynucleotides. Some patients benefit from pairing these treatments with PRP or gentle resurfacing, which can be discussed during your assessment:
https://alcoveaesthetics.com/PRP/
During Treatment
A small blood sample is collected for PRP. The under eye area is numbed to ensure comfort. Both PRP and polynucleotides are injected using fine needles or a cannula, depending on your anatomy and treatment goals. The process takes around 30 to 45 minutes.
After Your Visit
There may be mild swelling or tiny marks that settle within one to three days. Follow up appointments are offered to ensure your results progress as expected.
Recovery and Aftercare
Downtime is minimal. Most patients return to work the same day or the next day. You may experience:
- light swelling
- mild tenderness
- tiny pinpoint marks
These usually resolve quickly. Results develop gradually as collagen and tissue repair increase. For optimal recovery, avoid intense exercise, heat treatments and active skincare for 24 to 48 hours.
Cost and Transparency
Treatment plans are personalised. Individual sessions may include PRP at £350 and polynucleotides at £330, with package courses offering greater value. Many patients choose a combined approach for best results. A full consultation is required to determine suitability and create a tailored plan.
Frequently Asked Questions
Is it painful?
Most patients say the treatment is comfortable due to numbing cream and Dr Goziem’s gentle technique.
Is it suitable for everyone?
A consultation is required. Most patients benefit, especially those with fine lines, crepiness or dullness. Suitability depends on your medical history and skin condition.
How many sessions do I need?
Most patients need 2 to 3 sessions spaced a few weeks apart.
Can it replace fillers?
For many patients, yes. If your main concern is skin quality rather than volume loss, regenerative treatments can be a safer, more natural option.
Can it be combined with other treatments?
Yes. Treatments like Microneedling can be added to improve texture in the wider eye area:
https://alcoveaesthetics.com/microneedling/
To book your personalised consultation with Dr Goziem Onuchukwu at Alcove Aesthetics, Pall Mall, London, call 07856962248 or book online at alcoveaesthetics.com/appointments.
